Dr Souren Paul is a Cell and Molecular Biologist. He got his master degree in Botany with Biochemistry specialization. He won a gold medal for securing first class first in M.Sc. He has a PhD degree in Biotechnology from Daegu University, Korea. His research work focuses on molecular events of inflammation during cancer. He also worked on apoptosis/autophagy modulating bioactive compounds in cancer. Later, Dr. Souren moved to the USA to pursue his postdoctoral research. He continues his research on Cell and Molecular Biology focusing on telomere and centromere in cancer and stem cells. Dr. Souren has more than 25 publications including top journals like Nature Communications, Cancer Research, Cancer Letters, Inflammation Research, Free Radical Biology and Medicines, etc. Dr. Souren serves as a reviewer in more than 50 journals including Nature Communication, Scientific Report, Journal of Molecular Medicine, Journal of Chemotherapy, Clinical and Translational Discovery, etc. He is also serving as editor in Frontiers in Pharmacology, Frontiers in Cell Death, and Cancer. Dr. Souren is an associate member of the American Association of Cancer Research. He has been awarded the prestigious Ramanujan Fellowship.

Publications:

1. Souren Paul, M.H. Kaplan, D. Khanna, et al. and Contreras-Galindo R. Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis. Nature Communications; 13, 7074 (2022), https://doi.org/10.1038/s41467-022-34775-8.
2. Souren Paul1, Monika Bhardwaj, Sun Chul Kang1. GSTO1 confers drug resistance in HCT116 colon cancer cells through an interaction with TNFIP3/A20. International Journal of Oncology; 61(5):136 (2022). doi: 10.3892/ijo.2022.5426.1 Corresponding authors
3. Hisae Yoshitomi, Kun Lee, Ke Yao, Seung Ho Shin, Tianshun Zhang, Qiushi Wang, Souren Paul, Eunmiri Roh, Joohyun Ryu, Hanyong Chen, Faisal Aziz, Abhijit Chakraborty, Ann Bode, and Zigang Dong. GSK3B-mediated expression of CUG- translated WT1 is critical for tumor progression. Cancer Research (2021) 81(4):945-955.
4. Monika Bhardwaj, Na-Hyung Kim, Souren Paul, Rekha Jakhar, Jaehong Han, Sun Chul Kang. 5-Hydroxy-7-Methoxyflavone Triggers Mitochondrial-Associated Cell Death via Reactive Oxygen Species Signaling in Human Colon Carcinoma Cells. PLoS ONE; 11(4) (2016): e0154525.doi:10.1371/journal.pone.0154525.
5. Rekha Jakhar1, Souren Paul1, Monika Bhardwaj, Sun Chul Kang. Astemizole- Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis. Cancer Letters; 372 (2016) 89–100.1 Contributed Equally.
6. Souren Paul, Rekha Jakhar, Monika Bhardwaj, Sun Chul Kang. Glutathione-S- transferase omega 1 (GSTO1-1) acts as mediator of signaling pathways involved in aflatoxin B1-induced apoptosis–autophagy crosstalk in macrophages. Free Radical Biology and Medicine; 89 (2015) 1218-1230.
7. Monika Bhardwaj, Souren Paul, Rekha Jakhar, Sun Chul Kang. Potential role of Vitexin in alleviating heat stress-induced cytotoxicity: Regulatory effect of Hsp90 on ER stress-mediated autophagy. Life Sciences; 142 (2015) 36-48.
8. Rekha Jakhar, Souren Paul, Young Rong Park, Jaehong Han, Sun Chul Kang. 3,5,7,3',4'-Pentamethoxyflavone, a quercetin derivative protects DNA from oxidative challenges: Potential mechanism of action. Journal of Photochemistry and Photobiology B: Biology;131 (2014) 96–103.
9. Souren Paul, Sun Chul Kang. Natural polyamine inhibits mouse skin inflammation and macrophage activation. Inflammation Research; 62 (2013) 681–688.
10. Souren Paul, Heung Sop Shin, Sun Chul Kang. Inhibition of inflammations and macrophage activation by ginsenoside-Reisolated from Korean ginseng (Panax ginseng C.A. Meyer). Food and Chemical Toxicology; 50 (2012) 1354–1361.