Green Synthesis and characterization of selenium nanoparticles using gymnema sylvestre leaves extract and evaluation of their antibacterial activity against gram-positive and gram-negative pathogens

Student name: Ms Afreen Siddiqui
Guide: Dr Chaithanya Madhurantakam
Year of completion: 2023
Host Organisation: Integral University, Lucknow
Supervisor (Host Organisation): Dr Salman Khan

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Abstract:

Selenium is an important micronutrient trace element that plays a principal role in humans and animals, has been suspected to have essential health benefits. Nanoparticles have become a popular field of study due to their unique physical, chemical, and biological properties. Among these, selenium nanoparticles (SeNPs) have attracted attention due to their antioxidant, antibacterial, antifungal, and anticancer properties. The use of nanoparticles in various fields such as medicine, agriculture, and electronics has led to an increased demand for the development of eco-friendly and cost-effective methods. One such method is the green synthesis of nanoparticles using plant extracts. In recent years, the green synthesis of selenium nanoparticles (SeNPs) using plant extracts has gained significant attention due to its numerous advantages over conventional chemical methods. In this study, we report on the green synthesis SeNPs using medicinal plant leaves extract as a reducing and stabilizing agent. The secondary objective is to study the antibacterial and antifungal properties of the synthesized SeNPs. Synthesized selenium nanoparticles are characterized using SEM, TEM, FTIR, UV-vis, DLS and Zeta. Furthermore, their potential applications in nanotechnology and biomedicine are also discussed.

Keywords: Selenium nanoparticles, green synthesis, medicinal plant, antimicrobial, antifungal.